Streptococcal Immunity Is Constrained by Lack of Immunological Memory following a Single Episode of Pyoderma.

The immunobiology underlying the slow acquisition of skin immunity to group A streptococci (GAS), is not understood, but attributed to specific virulence factors impeding innate immunity and significant antigenic diversity of the type-specific M-protein, hindering acquired immunity. We used a number...

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Bibliographic Details
Main Authors: Manisha Pandey, Victoria Ozberk, Ainslie Calcutt, Emma Langshaw, Jessica Powell, Tania Rivera-Hernandez, Mei-Fong Ho, Zachary Philips, Michael R Batzloff, Michael F Good
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5222516?pdf=render