Matrix M H5N1 Vaccine Induces Cross-H5 Clade Humoral Immune Responses in a Randomized Clinical Trial and Provides Protection from Highly Pathogenic Influenza Challenge in Ferrets.

Matrix M H5N1 Vaccine Induces Cross-H5 Clade Humoral Immune Responses in a Randomized Clinical Trial and Provides Protection from Highly Pathogenic Influenza Challenge in Ferrets.

Highly pathogenic avian influenza (HPAI) viruses constitute a pandemic threat and the development of effective vaccines is a global priority. Sixty adults were recruited into a randomized clinical trial and were intramuscularly immunized with two virosomal vaccine H5N1 (NIBRG-14) doses (21 days apar...

Full description

Bibliographic Details
Main Authors: Rebecca J Cox, Diane Major, Gabriel Pedersen, Rishi D Pathirana, Katja Hoschler, Kate Guilfoyle, Sarah Roseby, Geir Bredholt, Jörg Assmus, Lucy Breakwell, Laura Campitelli, Haakon Sjursen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4493055?pdf=render

Internet

http://europepmc.org/articles/PMC4493055?pdf=render

Similar Items