Association of Hypomorphic P2X7 Receptor Genotype With Age

One of the main risk factors for brain diseases is aging. Recent studies have shown that aging is a progressive degenerative process associated with chronic low-level inflammation. The ATP-gated P2X7 receptor (P2X7R) plays an important role in inflammation and has been associated with different brai...

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Bibliographic Details
Main Authors: Juana Maria Sanz, Simonetta Falzoni, Mario Luca Morieri, Angelina Passaro, Giovanni Zuliani, Francesco Di Virgilio
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Molecular Neuroscience
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Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00008/full