Mitochondrial Respiration in Insulin-Producing β-Cells: General Characteristics and Adaptive Effects of Hypoxia.

To provide novel insights on mitochondrial respiration in β-cells and the adaptive effects of hypoxia.Insulin-producing INS-1 832/13 cells were exposed to 18 hours of hypoxia followed by 20-22 hours re-oxygenation. Mitochondrial respiration was measured by high-resolution respirometry in both intact...

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Bibliographic Details
Main Authors: Ingrid K Hals, Simon Gustafson Bruerberg, Zuheng Ma, Hanne Scholz, Anneli Björklund, Valdemar Grill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4581632?pdf=render