Immunoprotective efficacy of six in vivo-induced antigens against Actinobacillus pleuropneumoniae as potential vaccine candidates in murine model

Immunoprotective efficacy of six in vivo-induced antigens against Actinobacillus pleuropneumoniae as potential vaccine candidates in murine model

Six in vivo-induced (IVI) antigens-RnhB, GalU, GalT, Apl_1061, Apl_1166, and HflX were selected for a vaccine trial in a mouse model. The results showed that the IgG levels in each immune group was significantly higher than that of the negative control (P<0.001). Except rRnhB group, proliferation...

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Bibliographic Details
Main Authors: Fei Zhang, Sanjie Cao, Zhuang Zhu, Yusheng Yang, Xintian Wen, Yung-Fu Chang, Xiaobo Huang, Rui Wu, Yiping Wen, Qigui Yan, Yong Huang, Xiaoping Ma, Qin Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Microbiology
Subjects:
Actinobacillus pleuropneumoniae
Cellular Immune Response
Humoral Immune Response
IVI antigens
putative vaccine candidates
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01623/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01623/full

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