Zebrafish Models of Diamond-Blackfan Anemia: A Tool for Understanding the Disease Pathogenesis and Drug Discovery

Zebrafish Models of Diamond-Blackfan Anemia: A Tool for Understanding the Disease Pathogenesis and Drug Discovery

Diamond-Blackfan anemia (DBA) is a rare bone marrow failure syndrome characterized by red blood cell aplasia. Currently, mutations in 19 ribosomal protein genes have been identified in patients. However, the pathogenic mechanism of DBA remains unknown. Recently, several DBA models were generated in...

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Bibliographic Details
Main Authors: Tamayo Uechi, Naoya Kenmochi
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Pharmaceuticals
Subjects:
ribosome
diamond-blackfan anemia
zebrafish
disease model
drug candidate
Online Access:https://www.mdpi.com/1424-8247/12/4/151

Internet

https://www.mdpi.com/1424-8247/12/4/151

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