Meloxicam executes its antitumor effects against hepatocellular carcinoma in COX-2- dependent and -independent pathways.

Cyclooxygenase (COX)-2 is overexpressed in many types of cancers including hepatocellular carcinoma (HCC). Meloxicam, a selective COX-2 inhibitor, has shown potential therapeutic effects against HCC, but the mechanisms accounting for its anti-cancer activities remain unclear.Meloxicam inhibited the...

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Bibliographic Details
Main Authors: Xiaofeng Dong, Rui Li, Peng Xiu, Xuesong Dong, Zongzhen Xu, Bo Zhai, Feng Liu, Hongchi Jiang, Xueying Sun, Jie Li, Haiquan Qiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3968044?pdf=render