The phage T4 DNA ligase in vivo improves the survival-coupled bacterial mutagenesis

The phage T4 DNA ligase in vivo improves the survival-coupled bacterial mutagenesis

Abstract Background Microbial mutagenesis is an important avenue to acquire microbial strains with desirable traits for industry application. However, mutagens either chemical or physical used often leads narrow library pool due to high lethal rate. The T4 DNA ligase is one of the most widely utiliz...

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Bibliographic Details
Main Authors: Junshu Wang, Fapeng Liu, Tianyuan Su, Yizhao Chang, Qi Guo, Qian Wang, Quanfeng Liang, Qingsheng Qi
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Microbial Cell Factories
Subjects:
T4 DNA ligase
Microbial mutagenesis
Atmospheric and room temperature plasma (ARTP)
Polyhydroxybutyrate (PHB)
Online Access:http://link.springer.com/article/10.1186/s12934-019-1160-7

Internet

http://link.springer.com/article/10.1186/s12934-019-1160-7

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