Identification and functional analysis of choline transporter in tongue cancer: A novel molecular target for tongue cancer therapy

Identification and functional analysis of choline transporter in tongue cancer: A novel molecular target for tongue cancer therapy

We examined the functional characteristics of choline uptake in human tongue carcinoma using the cell line HSC-3. Furthermore, we explored the possible correlation between the inhibition of choline uptake and apoptotic cell death. Both choline transporter-like protein 1 (CTL1) and CTL2 mRNAs and pro...

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Bibliographic Details
Main Authors: Ryohta Nishiyama, Fumiaki Nagashima, Beniko Iwao, Yuiko Kawai, Kana Inoue, Arisa Midori, Tsuyoshi Yamanaka, Hiroyuki Uchino, Masato Inazu
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Journal of Pharmacological Sciences
Subjects:
Choline
Transporter
Tongue cancer
Apoptotic cell death
Caspase-3/7
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316300391

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http://www.sciencedirect.com/science/article/pii/S1347861316300391

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