Enriched monolayer precursor cell cultures from micro-dissected adult mouse dentate gyrus yield functional granule cell-like neurons.

<h4>Background</h4>Stem cell cultures are key tools of basic and applied research in Regenerative Medicine. In the adult mammalian brain, lifelong neurogenesis originating from local precursor cells occurs in the neurogenic regions of the hippocampal dentate gyrus. Despite widespread int...

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Bibliographic Details
Main Authors: Harish Babu, Giselle Cheung, Helmut Kettenmann, Theo D Palmer, Gerd Kempermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0000388