The Mechanism Underlying the Protective Effects of Tannic Acid Against Isoproterenol-Induced Myocardial Fibrosis in Mice

The Mechanism Underlying the Protective Effects of Tannic Acid Against Isoproterenol-Induced Myocardial Fibrosis in Mice

Tannic acid (TA) belongs to a class of complex water-soluble polyphenolic derivatives that show anticarcinogenic, antiinflammatory, antioxidant, and scavenging activities. Here, we investigate the protective effects of TA against isoproterenol (ISO)-induced myocardial fibrosis (MF) in mice. Mice rec...

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Bibliographic Details
Main Authors: Donglai Ma, Bin Zheng, Huiru Du, Xue Han, Xuan Zhang, Jianping Zhang, Yonggang Gao, Shijiang Sun, Li Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
tannic acid
cardioprotection
isoproterenol
toll-like receptor 4
nuclear factor κB
myocardial fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00716/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00716/full

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