Skeletal muscle differentiation evokes endogenous XIAP to restrict the apoptotic pathway.

Myotube apoptosis occurs normally during muscle development and aging but it can lead to destruction of skeletal muscle in neuromuscular diseases. Therefore, understanding how myotube apoptosis is regulated is important for developing novel strategies for treatment of muscle loss. We investigated th...

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Bibliographic Details
Main Authors: Michelle I Smith, Yolanda Y Huang, Mohanish Deshmukh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2658743?pdf=render