Infection of XC cells by MLVs and Ebola virus is endosome-dependent but acidification-independent.

Inhibitors of endosome acidification or cathepsin proteases attenuated infections mediated by envelope proteins of xenotropic murine leukemia virus-related virus (XMRV) and Ebola virus, as well as ecotropic, amphotropic, polytropic, and xenotropic murine leukemia viruses (MLVs), indicating that infe...

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Bibliographic Details
Main Authors: Haruka Kamiyama, Katsura Kakoki, Hiroaki Yoshii, Masatomo Iwao, Tsukasa Igawa, Hideki Sakai, Hideki Hayashi, Toshifumi Matsuyama, Naoki Yamamoto, Yoshinao Kubo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3192169?pdf=render