Improving the efficiency of genomic loci capture using oligonucleotide arrays for high throughput resequencing

<p>Abstract</p> <p>Background</p> <p>The emergence of next-generation sequencing technology presents tremendous opportunities to accelerate the discovery of rare variants or mutations that underlie human genetic disorders. Although the complete sequencing of the affecte...

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Bibliographic Details
Main Authors: Chen Zugen, Homer Nils, Funari Vincent A, Merriman Barry, O'Connor Brian D, Lee Hane, Cohn Daniel H, Nelson Stanley F
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/10/646