Membrane Binding, Cellular Cholesterol Content and Resealing Capacity Contribute to Epithelial Cell Damage Induced by Suilysin of <i>Streptococcus suis</i>

Membrane Binding, Cellular Cholesterol Content and Resealing Capacity Contribute to Epithelial Cell Damage Induced by Suilysin of <i>Streptococcus suis</i>

<i>Streptococcus</i> (<i>S.</i>) <i>suis</i> is a major cause of economic losses in the pig industry worldwide and is an emerging zoonotic pathogen. One important virulence-associated factor is suilysin (SLY), a toxin that belongs to the family of cholesterol-depe...

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Bibliographic Details
Main Authors: Désirée Vötsch, Maren Willenborg, Walter M.R. Oelemann, Graham Brogden, Peter Valentin-Weigand
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Pathogens
Subjects:
<i>streptococcus suis</i>
suilysin
pore-forming toxin
membrane repair
respiratory epithelial cells
cholesterol-dependent pore-forming cytolysin
Online Access:https://www.mdpi.com/2076-0817/9/1/33

Internet

https://www.mdpi.com/2076-0817/9/1/33

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