Frequency and patterns of second-line resistance conferring mutations among MDR-TB isolates resistant to a second-line drug from eSwatini, Somalia and Uganda (2014–2016)

Frequency and patterns of second-line resistance conferring mutations among MDR-TB isolates resistant to a second-line drug from eSwatini, Somalia and Uganda (2014–2016)

Abstract Background Pulmonary tuberculosis is a leading cause of morbidity and mortality in developing countries. Drug resistance, a huge problem in this contagious disease, is driven by point mutations in the Mycobacterium tuberculosis genome however, their frequencies vary geographically and this...

Full description

Bibliographic Details
Main Authors: David Patrick Kateete, Rogers Kamulegeya, Edgar Kigozi, Fred Ashaba Katabazi, Deus Lukoye, Sindani Ireneaus Sebit, Hergeye Abdi, Peter Arube, George William Kasule, Kenneth Musisi, Myalo Glen Dlamini, Derrick Khumalo, Moses L. Joloba
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Pulmonary Medicine
Subjects:
Tuberculosis
Fluoroquinolones
Aminoglycosides
gyrA/gyrB
rrs
16S rRNA
Online Access:http://link.springer.com/article/10.1186/s12890-019-0891-x

Internet

http://link.springer.com/article/10.1186/s12890-019-0891-x

Similar Items