Presence of Tablet Remnants of Nevirapine Extended-Release in Stools and Its Impact on Virological Outcome in HIV-1-Infected Patients: A Prospective Cohort Study.

Nevirapine extended-release (NVP-XR) taken once daily remains an effective antiretroviral agent for patients infected with HIV-1 strains that do not harbor resistance mutations. Presence of tablet remnants of NVP XR in stools was reported in 1.19% and 3.05% of subjects in two clinical trials. Howeve...

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Main Authors: Yi-Chieh Lee, Shu-Wen Lin, Mao-Yuan Chen, Sui-Yuan Chang, Ching-Hua Kuo, Wang-Huei Sheng, Szu-Min Hsieh, Hsin-Yun Sun, Hsi-Yen Chang, Mon-Ro Wu, Wen-Chun Liu, Pei-Ying Wu, Shang-Ping Yang, Jun-Yu Zhang, Yi-Ching Su, Yi-Zhen Luo, Chien-Ching Hung, Shan-Chwen Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4605833?pdf=render