Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation

Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation

The brain regulates physiological functions integral to survival. However, the insight into brain neuronal regulation of peripheral immune function and the neuromediator systems and pathways involved remains limited. Here, utilizing selective genetic and pharmacological approaches, we studied the ro...

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Bibliographic Details
Main Authors: Kurt R. Lehner, Harold A. Silverman, Meghan E. Addorisio, Ashbeel Roy, Mohammed A. Al-Onaizi, Yaakov Levine, Peder S. Olofsson, Sangeeta S. Chavan, Robert Gros, Neil M. Nathanson, Yousef Al-Abed, Christine N. Metz, Vania F. Prado, Marco A. M. Prado, Kevin J. Tracey, Valentin A. Pavlov
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
forebrain cholinergic
cytokines
inflammation
vagus nerve
endotoxemia
sepsis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00585/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00585/full

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