Glucose sensing in the pancreatic beta cell: a computational systems analysis
<p>Abstract</p> <p>Background</p> <p>Pancreatic beta-cells respond to rising blood glucose by increasing oxidative metabolism, leading to an increased ATP/ADP ratio in the cytoplasm. This leads to a closure of K<sub>ATP </sub>channels, depolarization of the...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-05-01
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| Series: | Theoretical Biology and Medical Modelling |
| Online Access: | http://www.tbiomed.com/content/7/1/15 |