A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers

A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers

Summary: Cancer progression to an aggressive phenotype often co-opts aspects of stem cell biology. Here, we developed gene signatures for normal human stem cell populations to understand the relationship between epithelial cancers and stem cell transcriptional programs. Using a pan-cancer approach,...

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Bibliographic Details
Main Authors: Bryan A. Smith, Nikolas G. Balanis, Avinash Nanjundiah, Katherine M. Sheu, Brandon L. Tsai, Qingfu Zhang, Jung Wook Park, Michael Thompson, Jiaoti Huang, Owen N. Witte, Thomas G. Graeber
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718313494

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http://www.sciencedirect.com/science/article/pii/S2211124718313494

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