MMP19 is essential for T cell development and T cell-mediated cutaneous immune responses.

Matrix metalloproteinase-19 (MMP19) affects cell proliferation, adhesion, and migration in vitro but its physiological role in vivo is poorly understood. To determine the function of MMP19, we generated mice deficient for MMP19 by disrupting the catalytic domain of mmp19 gene. Although MMP19-deficie...

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Bibliographic Details
Main Authors: Inken M Beck, René Rückert, Katja Brandt, Markus S Mueller, Thorsten Sadowski, Rena Brauer, Peter Schirmacher, Rolf Mentlein, Radislav Sedlacek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2386969?pdf=render