Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans

Abstract To assess the utility of autofluorescence as a noninvasive biomarker of senescence in Caenorhabditis elegans, we measured the autofluorescence of individual nematodes using spectrofluorometry. The fluorescence of each worm increased with age. Animals with lower fluorescence intensity exhibi...

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Bibliographic Details
Main Authors: Tomomi Komura, Mikihiro Yamanaka, Kohji Nishimura, Keita Hara, Yoshikazu Nishikawa
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:npj Aging and Mechanisms of Disease
Online Access:https://doi.org/10.1038/s41514-021-00061-y