Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice
<p>Abstract</p> <p>Background</p> <p>The mechanism by which HIV infection leads to a selective depletion of CD4 cells leading to immunodeficiency remains highly debated. Whether the loss of CD4 cells is a direct consequence of virus infection or bystander apoptosis of u...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-01-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/8/1/34 |