Synergistic protective effects of lycopene and N-acetylcysteine against cisplatin-induced hepatorenal toxicity in rats

Abstract Cisplatin (CP) is one of the most frequently used chemotherapy agents. The objective of this design was to determine the ameliorative effect of lycopene (LP) and/or N-acetylcysteine (NAC) in rats with hepatic and renal toxicity induced by CP. Rats were divided randomly into 7 groups (7 rats...

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Bibliographic Details
Main Authors: Asmaa Elsayed, Ashraf Elkomy, Reda Elkammar, Gehan Youssef, Ehab Yahya Abdelhiee, Walied Abdo, Sabreen Ezzat Fadl, Ahmed Soliman, Mohamed Aboubakr
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93196-7