Strategy for Leukemia Treatment Targeting SHP-1,2 and SHIP

Strategy for Leukemia Treatment Targeting SHP-1,2 and SHIP

Protein tyrosine phosphatases (PTPs) are modulators of cellular functions such as differentiation, metabolism, migration, and survival. PTPs antagonize tyrosine kinases by removing phosphate moieties from molecular signaling residues, thus inhibiting signal transduction. Two PTPs, SHP-1 and SHP-2 (S...

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Bibliographic Details
Main Authors: Fang Hao, Chen Wang, Christine Sholy, Min Cao, Xunlei Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SHP-1
SHP-2
SHIP
leukemia
AML
PTP inhibitor
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.730400/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.730400/full

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