The calcium‐sensing receptor: A novel target for treatment and prophylaxis of neratinib‐induced diarrhea

Abstract Diarrhea is one of the most commonly reported adverse effect of hemotherapy and targeted cancer therapies, such as tyrosine kinase inhibitors (TKI), which often significantly impact patient quality of life, morbidity, and mortality. Neratinib is an oral, irreversible pan‐HER tyrosine kinase...

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Bibliographic Details
Main Authors: Taras Lysyy, Alshad S. Lalani, Elizabeth A. Olek, Irmina Diala, John P. Geibel
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.521