Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity

Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity

The HCV replication cycle is tightly associated with host lipid metabolism: Lipoprotein receptors SR-B1 and LDLr promote entry of HCV, replication is associated with the formation of lipid-rich membranous organelles and infectious particle assembly highjacks the very-low-density lipoprotein (VLDL) s...

Full description

Bibliographic Details
Main Authors: Francisco J. Zapatero-Belinchón, Rina Ötjengerdes, Julie Sheldon, Benjamin Schulte, Belén Carriquí-Madroñal, Graham Brogden, Laura M. Arroyo-Fernández, Florian W. R. Vondran, Benjamin Maasoumy, Thomas von Hahn, Gisa Gerold
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
hepatitis C virus
SR-B1
LDLr
lipid metabolism
lipoprotein receptor
lipid-lowering drug
Online Access:https://www.mdpi.com/2073-4409/10/7/1626

Internet

https://www.mdpi.com/2073-4409/10/7/1626

Similar Items