Microvascular Structural Alterations in Cancer Patients Treated With Antiangiogenic Drugs

Microvascular Structural Alterations in Cancer Patients Treated With Antiangiogenic Drugs

Objective: Antiangiogenic therapies (tyrosine kinase inhibitors-TKI and direct anti-VEGF monoclonal antibodies) are being increasingly used in the treatment of solid tumors; hypertension represents a common side effect of these agents. Several mechanisms are involved in the development of hypertensi...

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Main Authors: Maria Antonietta Coschignano, Carolina De Ciuceis, Claudia Agabiti-Rosei, Valeria Brami, Claudia Rossini, Giulia Chiarini, Paolo Malerba, Francesca Famà, Deborah Cosentini, Maria Lorenza Muiesan, Massimo Salvetti, Alina Petelca, Sara Capellini, Chiara Arnoldi, Matteo Nardin, Salvatore Grisanti, Damiano Rizzoni, Alfredo Berruti, Anna Paini
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
VEGF
hypertension
microcirculation
small resistance arteries
capillaroscopy
retinal arterioles
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.651594/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.651594/full

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