Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming.

Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming.

Fair comparison of reprogramming efficiencies and in vitro differentiation capabilities among induced pluripotent stem cell (iPSC) lines has been hampered by the cellular and genetic heterogeneity of de novo infected somatic cells. In order to address this problem, we constructed a single cassette a...

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Bibliographic Details
Main Authors: Tomoyuki Yamaguchi, Sanae Hamanaka, Akihide Kamiya, Motohito Okabe, Mami Kawarai, Yukiko Wakiyama, Ayumi Umino, Tomonari Hayama, Hideyuki Sato, Youn-Su Lee, Megumi Kato-Itoh, Hideki Masaki, Toshihiro Kobayashi, Satoshi Yamazaki, Hiromitsu Nakauchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3399796?pdf=render

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http://europepmc.org/articles/PMC3399796?pdf=render

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