A fragmented alignment method detects a phosphorylation site and a new BRC repeat in the Drosophila melanogaster BRCA2 protein, and a new HAT repeat in Utp6 from yeast [v1; ref status: indexed, http://f1000r.es/1aq]
Mutations in the BRCA2 tumor suppressor protein leave individuals susceptible to breast, ovarian and other cancers. The BRCA2 protein is a critical component of the DNA repair pathways in eukaryotes, and also plays an integral role in fostering genomic variability through meiotic recombination. Alth...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2013-06-01
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| Series: | F1000Research |
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| Online Access: | http://f1000research.com/articles/2-143/v1 |