NKT cells as an ideal anti-tumor immunotherapeutic

NKT cells as an ideal anti-tumor immunotherapeutic

Human NKT cells are characterized by their expression of an invariant T cell antigen receptor (TCR)  chain variable region encoded by a V24J18 rearrangement. These NKT cells recognize -galactosylceramide (-GalCer) in conjunction with the MHC class-I-like CD1d molecule and bridge the innate and...

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Bibliographic Details
Main Authors: Shin-ichiro eFujii, Kanako eShimizu, Yoshitaka eOkamoto, Naoki eKunii, Toshinori eNakayama, Shinichiro eMotohashi, Masaru eTaniguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Induced Pluripotent Stem Cells
Clinical Trial
NKT cells
adjuvant effects
artificial adjuvant vector cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00409/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00409/full

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