Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype

<p>Abstract</p> <p>Background</p> <p><it>MMTV-Wnt1 </it>transgenic mice develop mammary hyperplasia early in development, followed by the appearance of solitary mammary tumors with a high proportion of cells expressing early lineage markers and many myoepith...

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Bibliographic Details
Main Authors: Li Yi, Podsypanina Katrina, Varmus Harold E
Format: Article
Language:English
Published: BMC 2004-06-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/2/24