Computational Evaluation of Nucleotide Insertion Opposite Expanded and Widened DNA by the Translesion Synthesis Polymerase Dpo4

Computational Evaluation of Nucleotide Insertion Opposite Expanded and Widened DNA by the Translesion Synthesis Polymerase Dpo4

Expanded (x) and widened (y) deoxyribose nucleic acids (DNA) have an extra benzene ring incorporated either horizontally (xDNA) or vertically (yDNA) between a natural pyrimidine base and the deoxyribose, or between the 5- and 6-membered rings of a natural purine. Far-reaching applications for (x,y)D...

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Bibliographic Details
Main Authors: Laura Albrecht, Katie A. Wilson, Stacey D. Wetmore
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Molecules
Subjects:
expanded DNA
xDNA
widened DNA
yDNA
DNA replication
translesion synthesis
bypass polymerase
Dpo4
molecular dynamics
Online Access:http://www.mdpi.com/1420-3049/21/7/822

Internet

http://www.mdpi.com/1420-3049/21/7/822

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