Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution

Background: NADPH oxidase 4 (NOX4) catalyzes the formation of hydrogen peroxide (H2O2). NOX4 is highly expressed in the kidney, but its role in renal injury is unclear and may depend on its specific tissue localization. Methods: We performed immunostaining with a specific anti-NOX4 antibody and meas...

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Bibliographic Details
Main Authors: Renuga Devi Rajaram, Romain Dissard, Anna Faivre, Frédérique Ino, Vasiliki Delitsikou, Vincent Jaquet, Thomas Cagarelli, Maja Lindenmeyer, Pidder Jansen-Duerr, Clemens Cohen, Solange Moll, Sophie de Seigneux
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719303039