Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis.

Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis.

The manifestation of coronary artery disease (CAD) follows a well-choreographed series of events that includes damage of arterial endothelial cells and deposition of lipids in the sub-endothelial layers. Genome-wide association studies (GWAS) of multiple populations with distinctive genetic and life...

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Bibliographic Details
Main Authors: Jörg Hager, Yoichiro Kamatani, Jean-Baptiste Cazier, Sonia Youhanna, Michella Ghassibe-Sabbagh, Daniel E Platt, Antoine B Abchee, Jihane Romanos, Georges Khazen, Raed Othman, Danielle A Badro, Marc Haber, Angelique K Salloum, Bouchra Douaihy, Nabil Shasha, Samer Kabbani, Hana Sbeite, Elie Chammas, Hamid el Bayeh, Francis Rousseau, Diana Zelenika, Ivo Gut, Mark Lathrop, Martin Farrall, Dominique Gauguier, Pierre A Zalloua, FGENTCARD Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3380020?pdf=render

Internet

http://europepmc.org/articles/PMC3380020?pdf=render

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