Cyclodextrin induces calcium-dependent lysosomal exocytosis.

Cyclodextrins (CDs) have long been used to manipulate cellular cholesterol levels both in vitro and in vivo, but their direct effects at a cellular level are not well characterized. Recently, CDs have garnered much interest because of their ability to clear stored cholesterol from Niemann Pick Type...

Full description

Bibliographic Details
Main Authors: Fannie W Chen, Chunlei Li, Yiannis A Ioannou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2993955?pdf=render