Histamine Modulates Midbrain Dopamine Neuron Differentiation Through the Regulation of Epigenetic Marks

Histamine Modulates Midbrain Dopamine Neuron Differentiation Through the Regulation of Epigenetic Marks

During midbrain development, dopamine neuron differentiation occurs before birth. Epigenetic processes such as DNA methylation and demethylation as well as post-translational modification of histones occur during neurogenesis. Here, we administered histamine (HA) into the brain of E12 embryos in viv...

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Bibliographic Details
Main Authors: Fernanda Vargas-Romero, Rodrigo González-Barrios, Lissania Guerra-Calderas, Itzel Escobedo-Avila, Daniel Cortés-Pérez, Adolfo López-Ornelas, Luisa Rocha, Ernesto Soto-Reyes, Iván Velasco
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
midbrain development
dopamine neuron differentiation
epigenetic modifications
neuroepigenetics
ultrasound-guided injection in utero
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00215/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00215/full

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