The Microbiome Activates CD4 T-cellâmediated Immunity to Compensate for Increased Intestinal PermeabilitySummary

The Microbiome Activates CD4 T-cellâmediated Immunity to Compensate for Increased Intestinal PermeabilitySummary

Background & Aims: Despite a prominent association, chronic intestinal barrier loss is insufficient to induce disease in human subjects or experimental animals. We hypothesized that compensatory mucosal immune activation might protect individuals with increased intestinal permeability from disea...

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Bibliographic Details
Main Authors: Karen L. Edelblum, Gil Sharon, Gurminder Singh, Matthew A. Odenwald, Anne Sailer, Severine Cao, Sarina Ravens, Irene Thomsen, Kamal El Bissati, Rima McLeod, Chen Dong, Sandeep Gurbuxani, Immo Prinz, Sarkis K. Mazmanian, Jerrold R. Turner
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X17300966

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http://www.sciencedirect.com/science/article/pii/S2352345X17300966

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