Delayed Start Protocol with Gonadotropin-releasing Hormone Antagonist in Poor Responders Undergoing In Vitro Fertilization: A Randomized, Double-blinded, Clinical Trial

Delayed Start Protocol with Gonadotropin-releasing Hormone Antagonist in Poor Responders Undergoing In Vitro Fertilization: A Randomized, Double-blinded, Clinical Trial

Objectives: We sought to determine the effects of the delayed start protocol with gonadotropin-releasing hormone (GnRH) antagonists in poor responders undergoing in vitro fertilization (IVF). Methods: This randomized clinical trial was conducted during a 15-month period from April 2014 to July 2015...

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Bibliographic Details
Main Authors: Afsoon Zarei, Mohammad Ebrahim Parsanezhad, Maryam Azizi Kutenaei, Bahia Namavar Jahromi, Parastoo Soheil Esfahani, Pardis Bakhshaei
Format: Article
Language:English
Published: Oman Medical Specialty Board 2018-11-01
Series:Oman Medical Journal
Subjects:
Iran. A total of 42 poor responders with primary infertility were randomly assigned to the controlled ovarian stimulation group utilizing the delayed start protocol (n = 21) or the traditional group (n = 21) using GnRH antagonist
Cetrotide. The primary endpoint was the number of patients undergoing oocyte pick-up
implantation
and the rate of pregnancy. Results: The baseline characteristics of the two study groups were comparable including age
infertility duration
and body mass index. The number of follicles measuring > 13 mm in diameter (p = 0.057)
retrieved oocytes (p = 0.564)
mature metaphase II oocytes (p = 0.366)
embryos (p = 0.709)
and transferred embryos (p = 0.060) were comparable between the two groups. The number of patients undergoing oocyte pick-up (p = 0.311)
the rates of implantation (p = 0.407)
Gonadotropin-Releasing Hormone
In Vitro Fertilization
Online Access:http://omjournal.org/articleDetails.aspx?coType=1&aId=2403

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