Identification of Distinct Tumor Subpopulations in Lung Adenocarcinoma via Single-Cell RNA-seq.

Identification of Distinct Tumor Subpopulations in Lung Adenocarcinoma via Single-Cell RNA-seq.

Single-cell sequencing, which is used to detect clinically important tumor subpopulations, is necessary for understanding tumor heterogeneity. Here, we analyzed transcriptomic data obtained from 34 single cells from human lung adenocarcinoma (LADC) patient-derived xenografts (PDXs). To focus on the...

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Bibliographic Details
Main Authors: Jae-Woong Min, Woo Jin Kim, Jeong A Han, Yu-Jin Jung, Kyu-Tae Kim, Woong-Yang Park, Hae-Ock Lee, Sun Shim Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4549254?pdf=render

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http://europepmc.org/articles/PMC4549254?pdf=render

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