Cellular senescence as the causal nexus of aging

We present cellular senescence as the ultimate driver of the aging process, as a causal nexus that bridges microscopic subcellular damage with the phenotypic, macroscopic effect of aging. It is important to understand how the various types of subcellular damage correlated with the aging process lead...

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Bibliographic Details
Main Authors: Naina eBhatia-Dey, Riya R Kanherkar, Susan E Stair, Evgeny O Makarev, Antonei Benjamin Csoka
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00013/full