High Glucose and Advanced Glycation End Products Induce CD147-Mediated MMP Activity in Human Adipocytes

Basigin (CD147) is a transmembrane glycoprotein that regulates several physiological processes, including the production and activity of matrix metalloproteinases (MMPs). The activity of CD147 depends mainly on its glycosylation, which varies among pathophysiological conditions. However, it is unkno...

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Bibliographic Details
Main Authors: Abeer M. Mahmoud, Mohamed M. Ali
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/8/2098