Changes in gene expression of lactate carriers (MCT1 and CD147) in cardiac muscle of diabetic male rats: the effect of dichloroacetate and endurance training

Changes in gene expression of lactate carriers (MCT1 and CD147) in cardiac muscle of diabetic male rats: the effect of dichloroacetate and endurance training

Lactate accumulation can activate the pathways of mitochondrial biogenesis in the heart muscle. The purpose of this study was to investigate the effects of Pyruvate Dehydrogenase Kinase 4 (PDK4) inhibition and endurance training on the gene expression of lactate carriers (MCT1 and CD147) in the card...

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Bibliographic Details
Main Authors: H. Rezaeinasab, A. Habibi, M. Nikbakht, M. Rashno, S. Shakerian
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2020-10-01
Series:Ukrainian Biochemical Journal
Subjects:
gene expression
diabetes
lactate
endurance training
dca
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2020/11/Rezaeinasab_5_20.pdf

Internet

http://ukrbiochemjournal.org/wp-content/uploads/2020/11/Rezaeinasab_5_20.pdf

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