EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP

EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP

Abstract Background Rituximab combined with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) is used as standard frontline regimen for diffuse large B-cell lymphoma (DLBCL). The landscape of somatic mutations in DLBCL revealed that inactivation of EP300 plays an important role in lym...

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Bibliographic Details
Main Authors: Jiao Li, Ning Ding, Xiaogan Wang, Lan Mi, Lingyan Ping, Xuan Jin, Yalu Liu, Zhitao Ying, Yan Xie, Weiping Liu, Yuqin Song, Jun Zhu
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Cancer Cell International
Subjects:
Diffuse large B-cell lymphoma
EP300
rs20551
Single nucleotide polymorphism
R-CHOP chemotherapy
Online Access:http://link.springer.com/article/10.1186/s12935-017-0439-1

Internet

http://link.springer.com/article/10.1186/s12935-017-0439-1

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