Caspase dependent apoptotic activity of polycyclic cage-like heterocyclic hybrids

Caspase dependent apoptotic activity of polycyclic cage-like heterocyclic hybrids

A small library of cage-like heterocyclic hybrids encompassing pyrroloisoquinolines, pyridinone and acenaphthene structural moieties have been synthesized and tested for their potential as anticancer agents against HCT116 and JURKAT cell lines. The results revealed that these cell lines are more sen...

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Bibliographic Details
Main Authors: Raju Suresh Kumar, Abdulrahman I. Almansour, Natarajan Arumugam, D. Kotresha, Janardhana Papayya Balakrishna
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Saudi Journal of Biological Sciences
Subjects:
Cage-like heterocyclic hybrids
HCT116
JURKAT
Apoptosis
Cell cycle
TUNEL Assay
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X20304484

Internet

http://www.sciencedirect.com/science/article/pii/S1319562X20304484

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