Long-Term Diabetic Microenvironment Augments the Decay Rate of Capsaicin-Induced Currents in Mouse Dorsal Root Ganglion Neurons

Individuals with end-stage diabetic peripheral neuropathy present with decreased pain sensation. Transient receptor potential vanilloid type 1 (TRPV1) is implicated in pain signaling and resides on sensory dorsal root ganglion (DRG) neurons. We investigated the expression and functional activity of...

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Bibliographic Details
Main Authors: Xingjuan Chen, Yaqian Duan, Ashley M. Riley, Megan A. Welch, Fletcher A. White, Maria B. Grant, Alexander G. Obukhov
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Molecules
Subjects:
ROS
Online Access:https://www.mdpi.com/1420-3049/24/4/775