Assessment of human immune responses to H7 avian influenza virus of pandemic potential: results from a placebo-controlled, randomized double-blind phase I study of live attenuated H7N3 influenza vaccine.

Live attenuated influenza vaccines (LAIVs) are being developed to protect humans against future epidemics and pandemics. This study describes the results of a double-blinded randomized placebo-controlled phase I clinical trial of cold-adapted and temperature sensitive H7N3 live attenuated influenza...

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Main Authors: Larisa Rudenko, Irina Kiseleva, Anatoly N Naykhin, Marianna Erofeeva, Marina Stukova, Svetlana Donina, Galina Petukhova, Maria Pisareva, Vera Krivitskaya, Michael Grudinin, Zhanna Buzitskaya, Irina Isakova-Sivak, Svetlana Kuznetsova, Natalie Larionova, Julia Desheva, Irina Dubrovina, Alexandra Nikiforova, John C Victor, Kathy Neuzil, Jorge Flores, Vadim Tsvetnitsky, Oleg Kiselev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3922724?pdf=render