Disulfide bonds within the C2 domain of RAGE play key roles in its dimerization and biogenesis.

Disulfide bonds within the C2 domain of RAGE play key roles in its dimerization and biogenesis.

The receptor for advanced glycation end products (RAGE) on the cell surface transmits inflammatory signals. A member of the immunoglobulin superfamily, RAGE possesses the V, C1, and C2 ectodomains that collectively constitute the receptor's extracellular structure. However, the molecular mechan...

Full description

Bibliographic Details
Main Authors: Wen Wei, Leonie Lampe, Sungha Park, Bhavana S Vangara, Geoffrey S Waldo, Stephanie Cabantous, Sarah S Subaran, Dongmei Yang, Edward G Lakatta, Li Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3524233?pdf=render

Internet

http://europepmc.org/articles/PMC3524233?pdf=render

Similar Items