Regulation of TRPM7 Function by IL-6 through the JAK2-STAT3 Signaling Pathway.

AIMS:Previous studies have demonstrated that expression of the TRPM7 channel, which may induce delayed cell death by mediating calcium influx, is precisely regulated. However, functional regulation of TRPM7 channels by endogenous molecules has not been elucidated. The proinflammatory cytokine IL-6 c...

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Bibliographic Details
Main Authors: Aifen Liu, Fengbo Zhao, Jing Wang, Yin Zhao, Zhenzhao Luo, Yan Gao, Jing Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4806911?pdf=render