Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling.

Retinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse livers, the current study identifies the bona-fide hepat...

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Bibliographic Details
Main Authors: Qi Zhan, Yaping Fang, Yuqi He, Hui-Xin Liu, Jianwen Fang, Yu-Jui Yvonne Wan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3499475?pdf=render